The cause of the disorder is unknown. However, be sure to take the dosage your doctor prescribes for you. If your muscle-related side effects dont go away or become severe, tell your doctor right away. Chylomicrons help your body, low-density lipoproteins (LDL), sometimes referred to as bad cholesterol, high-density lipoproteins (HDL), sometimes referred to as good cholesterol, triglycerides, which are a type of fat that are building blocks of cholesterol, Apo B (high levels of this protein are a sign of high cholesterol), non-HDL cholesterol (calculated by subtracting your HDL cholesterol level from your total cholesterol), were reduced by an average of 13% to 14% in people who used Zetia, ranged from not changing to being reduced by an average of 1% in people who used a placebo, were reduced by an average of 18% in people who used Zetia, increased by an average of 1% in people who used a placebo, decreased by an average of 13% to 14% in people who used Zetia alone, decreased by an average of 15% to 40% in people who used a statin alone, depending on the statin used, decreased by an average of 24% to 46% in people who used Zetia and a statin, depending on the statin used, ranged from decreasing by an average to 1% to increasing by an average of 4% in people who took a placebo, decreased by an average of 19% to 20% in people who used Zetia alone, decreased by an average of 20% to 54% in people who used a statin alone, depending on the statin used, decreased by an average of 34% to 61% in people who used Zetia and a statin, depending on the statin used. The dose of Zetia used for children is the same as the adult dose. The actual price youll pay for any of these drugs depends on your insurance plan, your location, and the pharmacy you use. The brand name for this drug combination is Vytorin. They can suggest ways to help relieve your side effects, or they may recommend a different treatment option for you. Forget HDL and LDL. This may increase your risk of side effects. Females who could become pregnant should use birth control while taking Zetia with a statin drug. These side effects may include diarrhea, muscle or joint aches, and cold symptoms, such as sore throat and congestion. * Zetia is also approved to treat these conditions in children ages 10 years and older. Zetia is FDA-approved to treat certain types of high cholesterol in adults and in children when used with a low-cholesterol diet. If you have questions about weight changes while using Zetia, talk with your doctor. The heartbeat increases with a feeling of the heart fluttering. 5.8k views Answered >2 years ago. Examples of statin drugs include atorvastatin (Lipitor) and simvastatin (Zocor). Symptoms of atherosclerosis may include confusion, fatigue (lack of energy), trouble breathing, or pain in your chest, arms, or legs. Phase IV trials are used to detect adverse drug . Clinical studies have shown Zetia to be effective for treating homozygous sitosterolemia when used alone. Below are examples of these side effects. Eating large meals can worsen hypotension in some individuals with dysautonomia (Mathias, 2000). If your liver function tests show increased liver enzymes called transaminases while youre using Zetia with a statin drug, your doctor may stop your treatment. Theyll likely suggest changes to your treatment plan. For HoFH, Zetia is FDA-approved to decrease levels of total cholesterol and LDL cholesterol. Youll also need to check your insurance plan, as it may only cover one or the other. Its not known if its safe to take Zetia while breastfeeding or if the drug passes into breast milk. Zetias mechanism of action is considered complementary to that of statins and fenofibrate. Side effects could occur in children who are breastfed by someone taking a statin drug. Lipitor contains the active drug atorvastatin. Zetia comes as a tablet that you swallow. tightness of chest or wheezing. Last medically reviewed on September 18, 2021. This can raise your levels of these drugs and increase your risk of side effects. Additionally, a change in weight is not a listed side . Cholesterol can also be found in foods such as eggs, cheese, and meat. If you would like to report to the FDA a side effect youve had with Zetia, you can do so through MedWatch. The actual price youll pay depends on your insurance plan, your location, and the pharmacy you use. Statins lower cholesterol by preventing your liver from making new cholesterol. However, skip your missed dose if its almost time for your next dose. stuffy nose. Postural orthostatic tachycardia syndrome (POTS) is a condition characterized by lightheadedness or dizziness when standing and a racing heart. Learn about side effects, dosage, uses, interactions, and more. Many rare diseases have limited information. You can use the study as a second opinion to make health care decisions. The heart beats faster to pump it up to the brain, but with little success. Or they may recommend a product you apply to your skin, such as hydrocortisone cream. You should also look for supplements from reputable manufacturers. However, if youre taking Zetia with a statin drug, youll need to avoid eating grapefruit or drinking grapefruit juice. Off-label use is when a drug thats approved to treat one condition is used to treat a different condition. Tell your doctor if youre experiencing bothersome side effects from Zetia. Different interactions can cause different effects. Zetia is contraindicated under the following conditions: Zetia tablets should be stored at a room temperature of 77F (25C) in a tightly sealed container away from light. These tests will look at your cholesterol levels and also your liver enzyme levels. These lists contain examples of serious side effects that can occur with Lipitor or with both drugs (when taken individually). In these groups, joint pain occurred in: The length of time that adults and children experienced joint pain while taking Zetia in these clinical studies isnt known. Learn more about some of the side effects that Zetia may cause. This in turn increases clearance of cholesterol from the blood. Get medical help right away, if you have any of the symptoms listed above. Below are medications that can interact with Zetia. But keep in mind that Zetia is used to reduce cholesterol levels in your blood. Nausea/Vomiting. No, stopping Zetia shouldnt cause any side effects. In fact, researchers have looked into using Zetia to treat hair loss due to a condition called alopecia areata. These include: Note: For more information about the potential negative effects of Zetia, see the Zetia side effects section above. Zetia contains the active drug ezetimibe. Clinical studies have shown Zetia to be effective for treating homozygous familial hypercholesterolemia when used with atorvastatin or simvastatin. Here is a list of conditions that the Food and Drug Administration (FDA) has approved Zetia and Lipitor to treat. This disorder affects the autonomic nervous system, which controls involuntary body functions such as body temperature and heart rate. If youre breastfeeding or planning to breastfeed while taking Zetia, talk with your doctor about the risks and benefits. And talk with your doctor if you have any questions about eating certain foods with Zetia. diarrhea. The bottom line: Zetia may cause fewer side effects than statins (though some clinicians might dispute that) but Zetia may cause muscle problems and other adverse reactions. For more information about how the drug is used, see the Zetia uses section below. Some people experience mild side effects with Zetia. Before starting a new medication, its a good idea to talk with a healthcare professional about any questions or concerns you may have. If you use Zetia and warfarin together, your doctor may want to monitor you more closely during your treatment. During Zetia treatment, your doctor will likely recommend blood tests. Hot and cold spells. Talk with your doctor to learn more about which medications are right for you. Cholesterol is a fatty substance found in the cells of your body. Zetia and Crestor are both brand-name drugs. If you need financial support to pay for Zetia, or if you need help understanding your insurance coverage, help is available. Taking Zetia with cholestyramine can decrease the amount of Zetia in your body. upper respiratory tract infection, including the common cold. If you develop liver problems, you may be more likely to experience side effects with Zetia. If youre sexually active and you or your partner can become pregnant, talk with your doctor about your birth control needs while youre using Zetia. POTS affects the body's ability to pump blood from the legs to the rest of the body while standing. Symptoms of liver damage include: If you have any of the above symptoms of liver damage, tell your doctor right away. More research is needed to know for sure. But, they can have side effects and might not be right for you. (For more information on the specific conditions Zetia can treat, see the Zetia uses section.). LDL cholesterol was reduced by 15% more in children who took Zetia and simvastatin than in children who took simvastatin alone. Watch Part 2 here: https://youtu.be/HPfo2QOa89YHello Friends! There arent any foods that have been specifically reported to interact with Zetia. I am a stay at home mama to a sweet baby girl, and wife to an amazing h. Common side effects may include: diarrhea; cold symptoms such as stuffy nose, sneezing, sore throat; pain in an arm or leg; joint pain; or. But the condition isn't well understood, and many patients are dismissed as having anxiety, delaying diagnosis. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. For information on the effectiveness of Zetia, see the Zetia uses section below. This means you should avoid foods that are high in cholesterol and other types of fat. Zetia (ezetimibe) is a prescription drug that treats high cholesterol in adults and children. (For information on side effects, see the Zetia side effects section above.). If you have unused medication that has gone past the expiration date, talk to your pharmacist about whether you might still be able to use it. This may be caused by genetics, smoking, not getting enough physical activity, or eating too many foods that are high in cholesterol. Examples of bile acid sequestrants include: Zetia inhibits the intestinal absorption of cholesterol and phytosterols, resulting in a decrease in the transport of intestinal cholesterol to the liver. Statin drugs may pass into breast milk. These symptoms could be life threatening and require immediate medical care. Sometimes brain zaps are also accompanied by dizziness, pain, or tinnitus, a ringing in the ears. joint pain *. How long a medication remains good can depend on many factors, including how and where you store the medication. Zetia is also available in a generic form called ezetimibe. You may wonder how often certain side effects occur with this drug, or whether certain side effects pertain to it. Learn about the common, mild, and serious side effects it can cause and how to manage them. However, you may need to avoid grapefruit if you take Zetia with a statin, another type of cholesterol medication. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. But some people have reported memory loss, confusion, and forgetfulness while taking a statin drug. Postural orthostatic tachycardia syndrome (POTS) is one of a group of disorders that have orthostatic intolerance (OI) as their primary symptom. Taking Zetia with a statin may cause this side effect. Zetia is a lipid-lowering compound used to treat high cholesterol.Common side effects of ezetimibe include diarrhea, abdominal pain, back pain, joint pain, muscle aches, and sinus infection ().. Serious side effects of ezetimibe include hypersensitivity reactions (including angioedema - swelling of the skin and underlying tissues of the head and neck - that can be life-threatening), skin rash . Cholesterol is made naturally in your liver. In most cases, these side effects should be temporary. Despite having lower total cholesterol than white people, African Americans are at greater risk of dying from heart disease. This active drug is also available as a generic medication. You may also want to check out the online communities at Bezzy. These lists contain up to 10 of the most common mild side effects that can occur with Zetia, with Lipitor, or with both drugs (when taken individually). If you feel dizzy from Zetia, it may help to take your dose at bedtime. Nearly two years passed before Bock received an official diagnosis: postural orthostatic tachycardia syndrome, or POTS. See the Zetia prescribing information for details. Zetia is metabolized in the small intestine and liver. While there's no cure, several treatments and lifestyle changes can help manage the symptoms of POTS. The effect of Zetia, atorvastatin, or simvastatin on other types of cholesterol levels in this study isnt known. The children took Zetia and simvastatin or simvastatin alone. If you have any questions about eating certain foods while taking Zetia, talk with your doctor. In clinical studies, Zetia has been found to be effective for treating mixed high cholesterol when used with fenofibrate. You can learn more about how we ensure our content is accurate and current by reading our. The phase IV clinical study analyzes which people take Zetia and have Constipation. Learn about alternatives like new drugs, A new class of self-injectable medications are showing promise in treating high cholesterol. POTS is a form of orthostatic intolerance that is associated with the presence of excessive tachycardia and many other symptoms upon standing. Sometimes doctors will recommend taking both a statin medication and Zetia for high cholesterol. It isnt known how long adults and children experienced diarrhea while taking Zetia in these clinical studies. weakness and fatigue (tiredness) headaches. Postural Tachycardia Syndrome (PoTS) is an abnormality of the autonomic nervous system (ANS). Its FDA-approved to treat certain forms of high cholesterol in adults and in children ages 10 years and older. If your doctor confirms you had a serious allergic reaction to Zetia, they may have you switch to a different treatment. For more information on these side effects, see Side effect details below. There arent any herbs or supplements that have been specifically reported to interact with Zetia. Weight gain isnt a side effect reported in clinical studies of Zetia. Here are a few questions to get your discussion started with your doctor: To get information on different conditions and tips for improving your health, subscribe to any of Healthlines newsletters. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. Over time, plant sterols can build up in your blood vessels and raise your risk of heart disease. But if they become more severe or dont go away, talk with your doctor or pharmacist. The Benary's Giants have large, double blossoms, 4 to 6 inches across, available in a rainbow of . Before trying something new, its common to look for written reviews about the experiences of others. Zetia may be used with statin drugs to treat the following conditions in adults: Statins are another class of medications used to lower cholesterol. (A class of drugs is a group of medications that work in a similar way.) In clinical studies that lasted 8 weeks, Zetia was compared with a placebo (a treatment with no active drug). Ezetimibe can cause the breakdown of muscle tissue . If youve had an allergic reaction to Zetia or any of its ingredients, you should not take Zetia. Zetia is available in a strength of 10 milligrams (mg). They may have suggestions depending on your weight and health goals. A generic drug is an exact copy of the active drug in a brand-name medication. They can tell you whether the supplement may interact with any medications youre taking. Homozygous sitosterolemia is a genetic condition caused by a mutation (change) in the genes that control how plant sterols are cleared from your body. This is a serious medical condition that, if left untreated, can lead to kidney damage. In studies, some people had to stop taking Zetia because of this side effect. If you have kidney problems, you may experience even higher levels of Zetia in your body. Energy Drinks, such as Red Bull, should be avoided in those with POTS. Medications in the fibrate drug class may increase the amount of cholesterol thats stored in your gallbladder. Talk with your doctor if you have questions about using Zetia to lower your triglyceride levels. It also helps keep the drug from harming the environment. Welchol is a prescription drug used to treat type 2 diabetes and high cholesterol. However, 0.3% of people who took Zetia alone experienced joint pain so bothersome that they had to stop treatment. This can cause Zetia to be less effective. Any time youre considering taking a supplement, its important to discuss this with your doctor or pharmacist. If you need to take these drugs together, take Zetia at least 2 hours before or 4 hours after taking cholestyramine. It also isnt known how many adults and children experienced joint pain in clinical studies of Zetia used to treat other conditions. Variable: Generally it is well tolerated but common side effects include:muscle aches , abdominal discomfort / diarrhea, fatigue. The side effects of Zetia in children are similar to the side effects in adults. Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. Symptoms of a mild allergic reaction can include: A more severe allergic reaction is rare but possible. Twelve weeks of treatment with Zetia and atorvastatin or simvastatin was compared with atorvastatin or simvastatin used alone. However, Zetia shouldnt be used with fibrate drugs other than fenofibrate. (Fenofibrate is a drug used to lower your triglyceride levels.). Postural orthostatic tachycardia syndrome (POTS) is a blood circulation disorder characterized by two factors: A specific group of symptoms that frequently occur when standing upright. You may experience muscle problems as a side effect of Zetia. Talk with your doctor if youre concerned about your risk of memory loss while using Zetia alone or with a statin drug. Ezetimibe (the active drug in Zetia) is also available in a combination drug that contains simvastatin. Lying down on the bed, and raising your legs. Talk with your doctor about any liver problems you may have and whether its safe for you to take Zetia. Zetia hasnt been studied in certain types of dyslipidemia, including Frederickson types I, III, IV, and V. Zetia is taken orally with or without food. They may suggest foods that can help lower your cholesterol and reduce your risk of weight gain. Then you can share this information with your doctor. You should always consult your doctor or another healthcare professional before taking any medication. Zetia can interact with several other medications. Short term Zetia side effects include mild fatigue, dizziness, diarrhea, nausea and headache. If youre using Zetia while sexually active with a female who could become pregnant, talk with your doctor about your birth control needs. Its a place where people with certain conditions can find support and connect with others. As with all medications, the cost of Zetia can vary. But if you have any symptoms that are ongoing or that bother you, talk with your doctor or pharmacist. If your doctor confirms you had a mild allergic reaction to Zetia, theyll decide if you should continue using it. Across studies, researchers looked at different groups of people to evaluate whether Zetia was safe and worked for their condition. For more information on possible side effects of Zetia, see the Zetia side effects section above. Treatment is targeted at relieving low blood volume or regulating circulatory problems that may cause the disorder. But over time, heavy alcohol use can damage your liver. If youve noticed memory problems while taking Zetia, talk with your doctor. 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